4-Hydroxyimino-piperidine-1-carboxylic acid tert-butyl ester
tert-butyl 4-(hydroxyimino)piperidine-1-carboxylate
CAS: 150008-24-5
Molecular Formula: C10H18N2O3
4-Hydroxyimino-piperidine-1-carboxylic acid tert-butyl ester - Names and Identifiers
4-Hydroxyimino-piperidine-1-carboxylic acid tert-butyl ester - Physico-chemical Properties
| Molecular Formula | C10H18N2O3 |
| Molar Mass | 214.26 |
| Density | 1.16g/cm3 |
| Boling Point | 333°C at 760 mmHg |
| Flash Point | 155.2°C |
| Vapor Presure | 2.7E-05mmHg at 25°C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
| Refractive Index | 1.521 |
4-Hydroxyimino-piperidine-1-carboxylic acid tert-butyl ester - Introduction
tert-butyl 4-(hydroxyimino)piperidine-1-carboxylate, also known as N-tert-Butyl-4-piperidinecarboxylic acid hydroxamate, is an organic compound.
The nature of the compound is a white crystalline powder, soluble in alcohol and chloroform, insoluble in water. Its chemical formula is C12H23N3O3, the relative molecular mass is 257.33.
The main use of this compound is as a pharmaceutical intermediate. It is often used in the synthesis of antiviral and anticancer drugs in drug synthesis and has important biological activities.
The preparation of this compound can be achieved by chemical synthesis. A common synthetic method is to react 4-aminopiperidine with tert-butyryl chloride to give 4-(tert-butyrylamino) piperidine, which is then reacted with aqueous ammonia to give 4-(hydroxyimino) piperidine. This product was finally reacted with tert-butoxic acid to give the target product tert-butyl 4-(hydroxyimino)piperidine-1-carboxylate.
Regarding safety information, this compound is an organic compound and requires attention to safe operation. It may be irritating to the skin, eyes and respiratory tract. If it comes into contact with skin, rinse immediately with plenty of water. In the process of use, should be equipped with protective glasses, gloves and protective masks, to ensure good ventilation conditions. Avoid inhaling dust or contact with substances. In addition, the compound should be stored in a dry, cool, ventilated place, away from fire and combustibles.
The nature of the compound is a white crystalline powder, soluble in alcohol and chloroform, insoluble in water. Its chemical formula is C12H23N3O3, the relative molecular mass is 257.33.
The main use of this compound is as a pharmaceutical intermediate. It is often used in the synthesis of antiviral and anticancer drugs in drug synthesis and has important biological activities.
The preparation of this compound can be achieved by chemical synthesis. A common synthetic method is to react 4-aminopiperidine with tert-butyryl chloride to give 4-(tert-butyrylamino) piperidine, which is then reacted with aqueous ammonia to give 4-(hydroxyimino) piperidine. This product was finally reacted with tert-butoxic acid to give the target product tert-butyl 4-(hydroxyimino)piperidine-1-carboxylate.
Regarding safety information, this compound is an organic compound and requires attention to safe operation. It may be irritating to the skin, eyes and respiratory tract. If it comes into contact with skin, rinse immediately with plenty of water. In the process of use, should be equipped with protective glasses, gloves and protective masks, to ensure good ventilation conditions. Avoid inhaling dust or contact with substances. In addition, the compound should be stored in a dry, cool, ventilated place, away from fire and combustibles.
Last Update：2024-04-09 19:05:46
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CAS: 150008-24-5
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Product Name: TERT-BUTYL 4-(HYDROXYIMINO)PIPERIDINE-1-CARBOXYLATE Visit Supplier Webpage Request for quotation
CAS: 150008-24-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 150008-24-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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